您好！歡迎訪問上海起發(fā)實驗試劑有限公司網站！
全國服務咨詢熱線:
15921799099
15921799099
簡要描述：Proteus BioSciences was founded in 2002 to develop innovative products to advance proteomic research. We specialize in discovering peptides and proteins with novel biological properties
產品型號：廠商性質：經銷商更新時間：2024-08-29訪 問 量：4442詳細介紹
PRODUCT #: 25-6790
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （MYO7A） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: | |
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （MYO7A） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） WB （0.5-1.0 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: Hasson, T. et al. （1995）, Proc. Natl. Acad. Sci. 92:9815-9819. Hasson, T. et al. （1997）, Journal of Cell Biology 137:1287-1307. Hasson, T. et al. （1997）, Cell Motil. Cytoskel. 37:127-138. Hasson, T. et al. （2005）, Cell Motil. Cytoskel. 62:13-26. | |
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （MYO7A） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: | |
| DESCRIPTION: Myosin-VIIa is one of the unconventional members of the myosin molecular motor superfamily that move along filamentous actin. The protein is expressed primarily in the inner ear, retina and testis. Defects in the myosin-VIIa gene （MYO7A） are responsible for Usher syndrome, characterized by hearing impairment, lack of vestibular function and progressive retinal degeneration.MYO7A mutations are are responsible for deafness in shaker-1 mice and in other model systems. In the inner ear, myosin-VIIa is required for assembly of stereocilia, the sensory structures necessary for detecting sound signals. | |
| SPECIES CROSS-REACTIVITY: | Human, mouse, rat, pig, avian, amphibian |
| APPLICATIONS/DILUTIONS: | IF （5-10 ug/ml） |
| SOURCE: | Rabbits were immunized with amino acids 880-1077 from the tail region of human myosin-VIIa. |
| FORM/STORAGE: | 50 ug （0.5 mg/ml） of affinity purified IgG with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. |
| References: | |
產品咨詢
電話
QQ咨詢
4006551678
當前位置：
地址：上海浦東川沙鎮(zhèn)川沙路6619號上海起發(fā)實驗試劑有限公司
郵箱：xs1@78bio.com
傳真：021-50724961